Ultrasound-Generated Nanoscale Mechanical Stimulation to Regulate Stem Cell Differentiation
Siddhesh Saigaonkar, Aditi Joshi, Akshay Kumar, Arka Roy Choudhury, Rudra Pratap, Ajay Tijore*
- ACS Nanoscience Au
Selective killing of cancer-associated fibroblasts by ultrasound-mediated mechanical forces
Gomathi Sankar, Arka Roy Choudhury, Rashmita Luha, Akshay Kumar, Ketan Kulkarni, Mingxi Yao, Rudra Pratap, Aravind Kapali, Ajay Tijore
- Biomaterials
Confinement Suppresses Mechanical Force-Mediated Cancer Cell Apoptosis
Alka Kumari, Akshay Kumar, Gao Xu, Kaustav Roy, Rudra Pratap, Andrew Holle, Ajay Tijore
- Small
Nanoscale Ligand Spacing Regulates Mechanical Force-Induced Cancer Cell Killing
S Manasa Veena, Dixiao Chen, Akshay Kumar, Rudra Pratap, Jennifer L. Young, and Ajay Tijore
- Nano Letters
Ultrasound-mediated mechanical forces activate selective tumor cell apoptosis
Ajay Tijore, Felix Margadant, Nehal Dwivedi, Leslie Morgan, Mingxi Yao, Anushya Hariharan, Claire Alexandra Zhen Chew, Simon Powell, Glenn Kunnath Bonney, Michael Sheetz
- Bioengineering & Translational Medicine
Mechanobiological Strategies to Augment Cancer Treatment
Alka Kumari, S Manasa, Veena,Rashmita Luha and Ajay Tijore
- ACS Omega
Cancer cells can be killed mechanically or with combinations of cytoskeletal inhibitors
Ajay Tijore, Bo Yang and Michael Sheetz
- Front. Pharmacol
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Scientific Excellence in Mechanobiology
Our research bridges engineering, biology, and medicine to uncover how mechanical forces influence cellular behavior and disease progression. Through peer-reviewed publications and global academic collaborations, the Mechanobiologics Lab contributes to advancing translational biomedical research.
